quarta-feira, 20 de setembro de 2017
A recent Review: "Recent advances in understanding the cellular roles of GSK-3" Cormier KW and Woodgett JR. Recent advances in understanding the cellular roles of GSK-3 [version 1; referees: 3 approved] F1000Research 2017, 6(F1000 Faculty Rev):167 (doi: 10.12688/f1000research.10557.1), showed some pathways to inactivate the enzyme. I´m trying to find other unusual way to inactivate GSK-3 because of our research about lithium and Alzheimer´s Disease. We used lithium microdose. In this Review Woodget sayd "Besides exploring the regulation of GSK-3 through association with scaffolding proteins and phosphorylation at S9/21, recent findings have explored GSK-3 regulation by other post-translational modifications". I´m very interested in this issue.
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